I have been using a WS 2010 since January of this year, and it has worked flawlessly. Two days ago, I rebooted my computer, and the unit would not update. I looked at the title bar up on top, and it says WS2010 Comm Port Error. I don’t believe that I have changed any settings. Any suggestions? 
Did you check in setup… control panel… comm port and make sure it was on the right one? (Generally that’s COM1).
How about checking the wires?
Reboot the computer again?
also check no other software accessing the station…or even another version of WD?